Carbon monoxide (CO) poisoning, whether intentional or accidental, occurs when one inhales the colorless and odorless carbon monoxide gas. Despite improved awareness and sensory alarms, multiple deaths occur each year.

CO binds to hemoglobin with 200 times the affinity of oxygen. CO also shifts the oxygen dissociation curve to the left (the Haldane effect), which decreases oxygen release to tissues. CO can also bind cytochrome oxidase aa3/C and myoglobin. Reperfusion injury can occur when free radicals and lipid peroxidation are produced.

Read more: Carbon Monoxide Poisoning

Gangrene is caused by the organisms "Clostridia". Gangrene is the death or decay of body tissue often occurring in limbs, caused by insufficient blood supply, usually following disease or injury.

Narcotizing Soft Tissue Infections are similar to Gangrene usually arises in ischemic tissue (oxygen poor), especially in patients with compromised defense mechanisms, such as diabetics.

Read more: Soft Tissue Infections

Osteoradionecrosis is radiation induced progressive deterioration of bone.

Osteoradionecrosis is a term derived from three (3) root terms.

  • Osteo - bone
  • Radio - radiation
  • Necrosis - death of tissue

Read more: Osteoradionecrosis

Radiation Injures are soft tissue injuries usually arising from exposure to radiation: secondary to treatment for malignancy. The use of radiation to treat cancers of the head, neck, and other areas of the body has become an acceptable method employed by physicians to help destroy tumors and masses. However, radiation not only destroys the targeted tumor, but it sometimes causes destruction to the surrounding soft tissue. When the surrounding non-cancerous soft tissue is damaged the condition is known as Soft Tissue Radionecrosis. Although having a similar etiology, soft tissue radionecrosis should not be confused with osteoradionecrosis, which affects the bone.

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Oxygen is a necessary component of healing process. When a skin graft is applied it requires certain oxygen tissue concentration for it to heal. If there is not enough oxygen in tissue, the skin graft will be compromised. Performing a non invasive circulation test called TCOM (transcutaneous oximetry) will show if the skin graft is compromised. If TCOM reading is below the healing threshold, Hyperbaric Oxygen Therapy is indicated. HBOT will give provide oxygen for the tissue to accept the skin graft and for wounds to heal. HBOT is very useful tool in the hands of a Wound Care Physician.

Patients with persistent wounds of the lower extremities, particular diabetics, frequently benefit from disjunctive HBO therapy. HBO therapy increases growth of new blood vessels and permits oxygen to dissolve directly into blood and be delivered to hypoxic sites that lacks oxygen necessary for wound healing.

Read more: Diabetic Foot Ulcers

We offer HBOT services for the patients with neurological disorders. It is believed by some in the medical community, that breathing 100% oxygen under pressure could improve conditions such as Cerebral Palsy and Stroke. These beliefs are based upon the pharmacological effects of oxygen and the ideology of the diseases.

Read more: Cerebral Palsy

The FDA recognizes oxygen for the treatment of hypoxia (insufficient levels of oxygen in blood or tissue). Additionally, some of the pharmacological effects (characteristic or properties of a drug) of oxygen are: Anti-eschemic (promotes blood flow), reduces edema (tissue swelling), and it promotes neovascularization (growth of new blood vessels).

Read more: Stroke

Burns present a multifactorial tissue injury that culminates in a marked inflammatory response with vascular derangement from activated platelets and white cell adhesion with resultant edema, hypoxia, and vulnerability to severe infection. Poor white cell function caused by the local environment exacerbates this problem. Hyperbaric oxygen therapy (HBOT) addresses each of these pathophysiological derangements, and can, therefore, make a significant difference in patient outcomes. These mechanisms of action have been discussed above.

Read more: Burns

Decompression Sickness: Also called the Bends: It is sometimes a fatal disorder marked by neuralgic pain, paralysis and breathing difficulty. It is caused by release of bubbles in the tissue, upon too rapid decrease in pressure after a stay in a compressed environment.

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